|INDIAN INSTITUTE OF SCIENCE EDUCATION & RESEARCH, MOHALI|
Assistant Professor (Chemistry)
Knowledge city, Sector 81, SAS Nagar,
Manauli PO 140306
Mob: +91 9915323141
Research Area: Physical Organic Chemistry
My broader research objectives are in utilizing the concepts of physical organic chemistry towards design, development and studies on reactive species, photoswitchable (functional) materials and drug candidates. A lot of emphasis will be given on basic research, particularly in the areas of synthetic organic chemistry, spectroscopy and photochemistry.
Matrix isolation infrared spectroscopy:
Photoswitchable functional materials: Azobenzenes are robust switchable molecules with varying switching kinetics depending on the substitutions. Manipulation in the switching rate and functions can be made by changing the substitution. My research interest in this regard will be to connect multiple azobenzene moieties to a linker molecule in creating a light controlled void or confined space that can be useful for a small molecule transporter. Systematic design, synthesis, photochemistry and spectroscopic studies with respect to switching and transporting behaviour will be the major components of this project.
Drug candidates for the anti-infective therapeutic area: Antibacterial agents are one of the important drug categories that provide immense value to the health and remedy for many otherwise widely transmittable diseases. Despite their success, bacteria always try to stay one step ahead by developing resistance and transferring it. As a result, finding new ways for combating the bacterial growth through inhibiting/stopping their cellular functions is very important. Bacterial fatty acid biosynthesis (FAB) blocking agents are one of the emerging areas in this regard. Systematic design, library synthesis with different scaffolds and biological studies on various pathogens will be part of this project.
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