IISER Mohali started its academic programme in 2007, with a batch of 25 students in the five year BS - MS Dual Degree Program.  The PhD Program was started in 2008 and  the Integrated PhD program was started in 2012.

IISER Mohali's fully residential campus is located in 125 acres of land given by the Punjab Government, in the Knowledge City at Sector 81, Mohali.