IISER MOHALI

Abstract:
Optical based spatio-temporal imaging of internal structures of objects of interest is a key modality in several domains of science and engineering. The propagation models and reconstruction algorithms used have similarities across application domains of interest; thus enabling multi-domain use of the computational heart of these schemes.

I will talk about two such fast emerging domains, (a) Optical fluorescence based optical and photoacoustic tomography as a possible substitute for nuclear medicine isotopes in functional biomedical imaging, and, (b) Atmospheric parameter retrievals using satellite data

(a) We will give a brief overview of fluorescence based optical and photoacoustic tomography. Static settings correspond to the imaged quantity of interest such as the absorption/scattering coefficient of a pathological tissue, not varying with time. In dynamic settings, such as those found in pharmacokinetic imaging, the time varying concentrations of injected fluorophores are spatio-temporally imaged, along with their underlying (pharmacokinetic) rates of leakage with respect to the tissue under investigation.

We will present our recent reconstruction results with a fluorescence photoacoustic tomographic framework for the dynamic pharmacokinetic tomography problem.

(b) We will also briefly introduce the radiative transfer equation (RTE) based atmospheric tomographic reconstruction problem and typical solution, and draw parallels with biomedical optical tomographic imaging. We will show some preliminary reconstructions of ours in atmospheric RTE tomography from simulated data.


Brief Bio:
Dr Naren Naik is a specialist in modelling and reconstruction algorithms for tomographic imaging. He is currently Professor with the Department of Electrical Engineering, as well as the Center of Lasers and Photonics, Indian Institute of Technology, Kanpur. His and his group’s research is about the development and analysis of reconstruction and tracking algorithms including post-reconstruction analysis; especially in limited data, dynamic, shape and multimodal tomography in biomedical imaging, atmospheric parameter retrievals in remote sensing and battlefield surveillance. Their major application thrust in the past few years has been on one hand in functional biomedical imaging with fluorescence optical and photoacoustic tomography, as well as electrical-impedance and impedance-acoustic tomography, and on the other hand with radiative transfer based atmospheric remote sensing.

Dr Naik has obtained his ME and PhD from the Indian Institute of Science, Bengaluru, from the departments of Electrical Communication Engineering and Instrumentation(now Instrumentation and Applied Physics) respectively. His post-doctoral research has been at the Vrije Universiteit Brussel, Belgium, and the University of Canterbury, New Zealand.