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Welcome to the webpage of the NMR Research Facility at IISER Mohali. We are situated in the Central Analytical Facility (CAF) building in the institute's new campus at Sector 81, Mohali. The facility currently houses two high-field FTNMR spectrometers: 400MHz & 600MHz, in a specially designed magnet hall. The facility caters to the research needs of IISER Mohali's faculty across the disciplines of physics, chemistry and biology. The mandate of the facility is to foster inter-disciplinary research using sophisticated multi-dimensional NMR experiments and to provide state-of-the-art experimental facilities in the region. The facility was inaugurated on March 03, 2010.
Click to view pictures of the inaugural function and entire installation process - NMR Research Facility photos
400MHz Spectrometer
Make: Bruker Biospin Switzerland
Model: Avance-III
Operational Aspects: 9.397 Tesla Field Strength, 54mm (narrow bore) ultra-shield plus superconducting magnet with two channel rf console. Variable temperature system. Linux workstation with dedicated spectrometer software package TopSpin. Separate off-line Linux workstations for data processing and plotting of spectra.
Probes:
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Dual 1H/13C 5 mm probe with Z-gradient
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Universal BBFO 5mm probe with Z-gradient (19F observation/Any nucleus in range 31P to 15N)
Special Provisions: Automatic micro-processor based sample changer with capability of up to 60 samples
Applications: Structural analysis of chemical compounds containing NMR active nuclei. Screening of potential drugs. NOE and chemical exchange experiments.
Rates (per sample) for 400MHz NMR Spectrometer
Academic Institutions:
1D 1H experiment : INR 600
1D 13C experiment : INR 800
2D experiments, nuclei other than 1H/13C, low temperature experiments: INR 1500
Industry Users:
1D 1H experiment : INR 2000
1D 13C experiment : INR 3000
2D experiments, nuclei other than 1H/13C, low temperature experiments: INR 5000
600MHz Spectrometer
Make: Bruker Biospin Switzerland
Model: Avance-III
Operational Aspects: 14.1 Tesla Field Strength, 54mm (narrow bore) ultra-shield plus superconducting magnet with three channel rf console and digital lock. Multi-dimensional NMR experiments with decoupling facility. Variable temperature system. Linux workstation with dedicated spectrometer software package TopSpin. Separate off-line Linux workstations for data processing and plotting of spectra.
Probes:
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Triple nuclear inverse 1H/13C/15N 5mm probe with Z-axis pulsed field gradient
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Inverse broadband 5mm probe with Z-axis pulsed field gradient
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Four channel double resonance 19F/31P/13C 5mm probe with Z-axis pulsed field gradient and 1H decoupling
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HRMAS dual inverse 1H/13C 4mm probe with MAS unit and rotors
Applications: Protein structure determination (of isotopically labeled proteins). Protein dynamics, protein-ligand interactions and screening for ligands. Protein folding studies. Macromolecular protein-protein and protein-RNA/DNA complexes. Metabonomics/metabolomics. NMR Quantum Computing. Diffusion studies using gradient NMR.
Rates (per sample) for 600MHz NMR Spectrometer
Academic Institutions:
1D/2D Expts QXI/TXI probe : INR 2500
VT/Titration/Exchange QXI/TXI probe: INR 4000
HRMAS probe: INR 5000
3D Expts QXI/TXI probe: INR 7500
Industry Users:
1D/2D Expts QXI/TXI probe : INR 5000
VT/Titration/Exchange QXI/TXI probe: INR 6000
HRMAS probe: INR 7000
3D Expts QXI/TXI probe: INR 10000
Points to Note:
18% GST is applicable in addition to these base charges
Deuterated solvents for all samples must be provided by the user.
For more information contact:
Professor Kavita Dorai (Convenor 600Mhz NMR)
Department of Physics
Indian Institute of Science Education & Research (IISER) Mohali
Sector-81 S.A.S. Nagar Mohali, Manauli PO 140306, Punjab India
Telefax: +91-0172-2240266
Email: kavita(AT)iisermohali.ac.in
Sample submission form:
Internal users: |doc format| |pdf format|
External users: |doc format| |pdf format|
Mode of Payment: Via cheque/crossed DD in favour of Registrar IISER Mohali
Samples submitted to the NMR Facility are the property of the investigator. All data recorded by the NMR Facility directly relevant to the samples are released to the principal investigator upon completion of work. The NMR Research Facility at IISER Mohali should be acknowledged in all publications arising out of the work.
International Conference on NMR at the interface of physics, chemistry and biology November 29-30 2010, IISER Mohali
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