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Riddle wrapped in a mystery inside an enigma: How the transposon Tad survived in only one Neurospora strain
Wednesday 25 September 2024, 05:30pm

Prof Durgadas Kasbekar, INSA Senior Scientist at Centre for DNA Fingerprinting and Diagnostics (CDFD), Hyderabad

Location : LH3: Lecture Hall Complex
Abstract: No DNA sequence > ~ 250 bp is present in more than one copy in the Neurospora genome. A mutational process called RIP (repeat-induced point mutation) alters any duplicated DNA sequence by peppering all copies of it with multiple G:C to A:T transition mutations. However, one Neurospora strain, isolated from Adiopodoumé, Cote d’Ivoire, Africa, contains multiple copies of a transposable element (named Tad). How did Tad survive in this one strain?

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