Our recent collaborative work with Prof. Parthapratim Munshi and Dr. Craig Robertson has been published in CrystEngComm as a cover page article entitled "Organic fluorine mediated intermolecular interactions: insights from experimental and theoretical charge density analyses" (https://pubs.rsc.org/en/conte nt/articlelanding/2025/ce/ d4ce00829d). Herein we have demonstrated the importance of type II C–F⋯F–C interaction in crystal engineering through experimental and theoretical electron density analysis using very high-resolution X-ray diffraction data collected on a rotating anode-based X-ray diffractometer at The University of Liverpool, UK. Our qualitative and quantitative analyses demonstrated the stabilizing nature of the type II C–F⋯F–C interaction in the presence of weak C–H⋯F–C hydrogen bonds. We also established that these interactions are attractive, directional, and actively contribute to stabilizing the crystal structure.
Thanks to Yohita and K Krishna Mohan of SNUIoE for their help with this artwork conveying the theme of unraveling the attractive nature of organic fluorine-mediated intermolecular interactions in molecular crystals via electron density modeling of ultra-high-resolution X-ray diffraction data.